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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21a1803cc75307485532f41158563c04535b7b8623bbe8c73d1f82c732b9b3b' 
  AND token = 'r/fm+QIGYlmpFO2RP2GOs6ORJUnkxSh5o92yteuASDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}