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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c77619c37697cada796346cfc5eecf1739f74c00bdb0e91c7d1b7921ca2ba81f' 
  AND token = '+T2rwUK/Icp1MTDTUSDAyQCpm3tIvSZBFsGzWatf5sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}