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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6e09bc763a2c2120d5538bdfe37d2873ee0dc55e5f5366640825020d3e4a0a' 
  AND token = '992VjFO0FhUD57XdyTJSapoEBWpZAxzFpTlzNcWj4uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}