SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4118b8e5576998b31882f1e1620a216f5129fd84b65050f1689bd0ccf89c6c22' 
  AND token = 'HrMheMQcpuOrxMmfpjdhcO0AhV7x84Ae4nhGQwHjGdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}