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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfdc3aed4386d06ceab2958b55395f3d710e9e4d5effb205ed17876f1171a843' 
  AND token = '1QnEy32oKj5Os+2GuI5pmtBTG4Boc/bZ6Ddrujyip5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}