SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27aa51778f3912d89dcd280cb14d1e1c445fc00e6793eebd63cb807a1fcbff5d' 
  AND token = 'DbRPLZxV38iMcM/U2TBHf7g/SrPWDcX5cmkHgWlg61w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}