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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8410a23d9910396567807c1a32b3df98525338a703eafd8b5577d335d569e67c' 
  AND token = '7LLS2fxCmWSi4gzRUP8v+kevUucwEQBFstNiZb9uLuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}