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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3d68f57c8a4752819ea8fc2b553cd58da1cf36cfc2d439fea003bb93abd0c85' 
  AND token = 'oE6pqZoVGiDMsKPQq2+FEn7e2JGslSlVKjr6MduV5I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}