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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b563855b0f8ceced33fc94c6f5a80468697fbd74e700f3ccc64143be38b46f5c' 
  AND token = 'Rz819kxyLbG5/UIW4VsoaJD3P/J6lqj3ootipyT0Ox8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}