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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8fe41c5f5e423743b93885df9e502b17b4b50ce9c31faffccd53a821f281250' 
  AND token = 'LM5imf1kpZxEXh2i3H6e+vDxI33+W2zPMCzC80UzXZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}