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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6192ee2a4ea5b59c0a4f1ca898ad650a1927cc61d2e143f79a8d0d0377dbe656' 
  AND token = '8lvkZd0Di5XiDoXPz+rQmMIabbxM8KmkGosfQFYDDCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}