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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54eb6858e9abb9969fec3c5f8dd2a9bedb908ebcdd4aa71ed27b1f5595524746' 
  AND token = 'rSVV6T/LObNTgCKyHfMfyx5fp+hiQ4tBZCYIE+xSH60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}