SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448329284ed1f060a9a70b8c2a67b8263d8f6cf8a1f1a3eb64b6c7aca1e57670' 
  AND token = 'OyG6Ukyx1s2IkvHTQaU4oJJMXd638X9MvMR/xW4gInI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}