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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8270fea0a7ae6788c28cfc0ca91e4487f56c467a4e7f60cacef900bdecad1d07' 
  AND token = 'Pwgp2loNIQe9z/GwVCOevwr60p5BzkymSa81A0ewdCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}