SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a0de414e9aa03147c2a6d2dea6c5d51f89db1e60ee21b03d8bb983b79c0589' 
  AND token = '+f+3AgM7snDDJUPcJULYu9s35ZbnTH9jxDucvK9VfNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}