SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7dfeb710c85063edddd9b282f040368e4c45af8dc500076a7f5d607e5dd942' 
  AND token = 'nFHFOeJhNgzW3u59TioarWnO2FmqpVAnNbM6CuE4Wto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}