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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b215db3456f2e0d5878f487454fe5a64e7931f6084a1c7b9b8f8fbb09dfc3c2' 
  AND token = 'GwOta2eR2a8uEH5qgrXz3r+XC67zdXn5U+JNwdP230Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}