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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e95c4f2ace79f38c795c4c517bf1b37526717e437df3cef3d2c02986b0a3995' 
  AND token = '1+HFfguJCiaUV6U3dvXVw24Rt7sfgRMIa1mfovQiKb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}