SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6cfbd1f04a8fa866bdd88cd4fb209d231402bb624f4211547155d126ef1c514' 
  AND token = 'edxpJQHjbZ/zD3fE4OKN6UqYX57ERVWSrDRQkSZ4L6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}