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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08a072ae639068f829c63306ea5a3fc075812d1c50523c32eeef1e097eca3e55' 
  AND token = 'rbaQ3u2MFMPeAhDdq47XPyiIRYFe8IYmA+QJLtpGpLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}