SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d25f8563644496043635b56fc66f186c2c524b3478c7c718dbd6aed73998e51' 
  AND token = '9GTmrM5ZkYmdj6PUVZTpk9EmmrC02f5iBZWVwSEqaF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}