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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50cc44a2103ae6b4897c220be3f911a653235131fc95aa4b2d13e22521ff99b8' 
  AND token = 'bsCgK3EsYF4CJwgkHi42A70GZaWumFZwaKQenP9FZO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}