SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418bc9ec794b514a507095809876c11f714a05b0f3ff78880805a5d919e62546' 
  AND token = 'F1v4QM3UTwk4YbqhMoI9wTiWhaBb+qlIE639bWmunf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}