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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4c6db6f555f55712951b299477f9c5c529d7c96e8084e2479272481ff3fe16' 
  AND token = 'JQIixpFMduQeWHbT760B/qr4Z80eon62WaOjHErOxFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}