SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d4b13da626193f7a27dc3a3fb93a1302f82819e7453a8363cb26f35436d7da' 
  AND token = 'E/okDmEXwrGIRyzPm9LwgISqz9kgSYc9+Pd2YJraFeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}