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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c2ed2b9cf0d4649c05675b3876d51ec51863325251a72a88af62d5b71c562f' 
  AND token = 'mOFx/pi6zAe5qdzX8JiM/TmCa+uHUnapeWBZcO+GbOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}