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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd683b4b3c439de21b1056cec66c3b76b20fc7137e8e84d6cb8d6319c7c24f59' 
  AND token = 'ZEjEGKqWqtVafwLaFaIgt5gOVMR/D40GqOi4oIXGcG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}