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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c73de16cc17afb77c983adc0eace392376e150c071f09dfd5c4b11bda30e85' 
  AND token = 'Rl3aLF9kFm7XQLjtzn/DguwyVJuo9mqsHSdiyIyGRZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}