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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41c37d325ec2810fba12afd2d7e46b373ebd23529152af4b78fb80241136100' 
  AND token = '46cqnXm++gRHYvnnNcaFs39n2cKmTZEpN3J4lhQYD44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}