SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40486e8e7b46acbd6e9095f40063d0abaaee6548ce1e9cb0afee63c820626189' 
  AND token = '5gLYEL7x8w2iCXEdqLrcK1BxBsr95zeQDKHULZ1FDhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}