SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a9adfa9f8e13d7aaff9fef90e524b0acd223913effb10d8e17454b377d81c2' 
  AND token = '3t8sJ/2RGS6d9HfInp3RHxcNEBibp2qWCvJQ4/BGs54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}