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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0271a8fb41eaeb49a4100d28db92f83b6f04818230258fd99bce91a70edd9cec' 
  AND token = '4OIadxdxgEHVTXmnp3qauntBJlpnNzUNJu74M+L9cCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}