SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cb845d407cc24e1b9213b9308e41c025d30b6b728a4fb264f56c2f4e772936' 
  AND token = 'YZJ9buiqK3n0PeZafh+jHj2ZHeSyiQ2XLsYNu9ZjXWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}