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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe82c15f3519abf53d4861d284a335bc786bcd221aef6b5f96519bd455f40e4' 
  AND token = 'pMsnshb0K37lsYVhZP6wX5/u8sr645vPe0apBT9zMKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}