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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0879da4cd08d1a787cc807615e1f26d07c8e2d276c3cd83dd9117fabfabb56a' 
  AND token = 'GYTTTeSbjsij02FSMRfKdcJiqHaFP9U4+IQYVIsQl9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}