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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3adc2037e3b012327c89efb703221896b65a3898126b02a92c7883417a771c8f' 
  AND token = 'QewF9YAUASruh07Vmqdj8sxoUoNHNw97LKT5V1Kw4qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}