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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a95142d2748624eaa7e14f4bee71c3e8f443a7a15b42648b0c8b33be1365232' 
  AND token = 'zxUgpf1g44tacKcOUvd0pzcH0K0it5W1q+1CXuolI6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}