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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66c3800eb968a39e60b93f20656561914f553e0ed19f4693d58145dd9c7f392' 
  AND token = 'HC4tpONciU+jEz0dLXIyvDQbpuf3a+AIRZxMbr3wKl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}