SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e182cfab7506290715d90a806b8b598b534edceb898883c479fc8c05a861dc95' 
  AND token = 'FwzXnShiQY2Qc01nAMLLwxZgQW5+8JvsfwLL7JZY6eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}