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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f3e2d8432881663d1ab17db4b549afd7f09f680eee0cbca0e6011d4b0ecc71' 
  AND token = 'kqYWLzI38cgWi1JTzdMI/BlVGZFk2dF4jetkNtiT2n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}