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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c1bee6a9a8733a79da521bf7df2016166233c58b1430ee1a4a4a44f6d46c1de' 
  AND token = 'oCmJMVuPT+Efz+VnkmAi5JVA0m8ZuuUYHFOs5yWzrXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}