SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc140243358d8d0e08966e3602b537ab56fb745d9d0fb81e42b7e0dbff06249' 
  AND token = 'D8aJ0I3qF5TiNUsW9wlpI2MsH+nNVVHWUXsM/9qfwvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}