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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5377063bc49ff670c2fcc243d128bf26f0310e1f058d441440a84e79b741cbdc' 
  AND token = 'NoNvuFnCKi6KzahcNrqpRPYiC8LgWt+6SpsNZiup9Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}