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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3444b2a5a2d4550ff57158f329e11f985570c75d3a2de7cd0f1af99a97875850' 
  AND token = '8YK0yIpRjyn7eiVbkdjgOW5tM3ZtvKyA+6I9CpXypbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}