SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722332b5bfbe5907cd085c3cbfb1f5870b5be02f58812a862b25bd14c2cd2452' 
  AND token = 'zrKdE5+n9XLHPAUgQyX+r+J0BB4FUkhGH2noTm2d+Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}