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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9197964b08a0acab3f3fb172684e612513ba5b6bb4a0f0c9cb095158b79caf' 
  AND token = 'lJ3GASqL3Sbs8EoRrO8DOcTlPwsJBomiSTTHczwQyLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}