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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '786fd0b3747b0a755cfec2bfe3c7c721de6a90f1fff986a6a8525c653713a744' 
  AND token = 'LCV0UHbYt4CjLfU8Q4Wfp6XNVgl+TYIA3sYhFk2J0XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}