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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb38ae3115421989117bf8f4cee8c876a521fe8c80e760dc7d90bb7e15bfa3ac' 
  AND token = 'Qx2pegPgOtvRp613Ucwzxrgz+56UGDV0e/np4EiuJNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}