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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b881d640e29946d40a6a607f795dd9cd18799a1296bff2d77a7691e07da29174' 
  AND token = 'KU1povyHcux4WBX+Hu7micsZ13HVTLXA0lqRqMOI1Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}