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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c208ef79c649344ade1ed6d3f1dfaf170ed5f410e38c1f793c1f2987d2fc890' 
  AND token = 'v5ijnBFJo+T/x57YXcZHtCFRA9NMsFQqkfznGi7dR+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}